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Probability distributions are a key component of clinical research. One only has to make a cursory review of clinical literature to realize that nearly all clinical publications reference some sort of statistical test; be it t-test, chi-squared test, or [...]

A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions [...]

Mathematical modeling and computer simulation have proved tremendously
successful in engineering. One of the greatest challenges for mechanists is
to extend the success of computational mechanics to fields outside
traditional engineering, in particular to [...]

The itkLabelGeometryImageFilter is a new ITK filter that enables the measurement of geometric features of labeled objects. It calculates features similar to the "regionprops" command of Matlab. It is related to the itkLabelStatisticsImageFilter in that both [...]

Creating a 2D Active Shape Model Using itk::ImagePCAShapeModelEstimator
Published in The Insight Journal
Published in The Insight Journal
Although many variations of active contour segmentation algorithms exist, most are based on solely edge criteria and breakdown or leak at weak boundaries. One solution to this problem is constraining the segmented area to only statistically possible shapes [...]

Coupling Finite Element and Mesh-free Methods for Modelling Brain Deformation in Response to Tumour Growth
Published in The MIDAS Journal
Published in The MIDAS Journal
Very little is known about the deformation effects of tumour growth within the brain. Computer simulations have the potential to
calculate such deformations. A method for computing localised high deformations within the brain's soft tissue is presented. [...]

Realistic And Efficient Brain-Skull Interaction Model For Brain Shift Computation
Published in The MIDAS Journal
Published in The MIDAS Journal
In this paper we propose the usage of a very efficient contact implementation for modeling the brain-skull interaction. This contact algorithm is specially design for our Dynamic Relaxation solution method for solving soft-tissue registration problems. It [...]

3D Voxel-Based Volumetric Image Registration with Volume-View Guidance
Published in The Insight Journal
Published in The Insight Journal
In this article, we will present a novel interactive image registration technique using the 3D volumetric view as guidance throughout the registration process. The registration criterion used in this technique is the homogeneity of the color distribution on [...]
